Biology

Hardy Weinberg Principle

Describe allele and genotype frequencies under ideal population conditions.

p + q = 1; p² + 2pq + q² = 1

Formula Explanation

Under Hardy-Weinberg equilibrium, allele frequencies remain constant across generations when the required assumptions hold.

Variables Explained

p = Frequency of one allele; q = Frequency of the alternative allele; p² and q² = Homozygous genotype frequencies; 2pq = Heterozygous genotype frequency.

Solved Example

If q = 0.2, calculate p and 2pq.
p = 1 - 0.2 = 0.8. Therefore, 2pq = 2 × 0.8 × 0.2 = 0.32.

Exam Tip

Check that p + q = 1 before calculating genotype frequencies.